on PinterestNew GLP-1 ads, like telehealth provider Ro’s new campaign featuring tennis icon Serena Williams, aim to shift the conversation about weight loss drugs.
- This year, the Super Bowl will feature advertising of GLP-1 drugs in new ways.
- Telehealth provider Ro is using tennis star Serena Williams to help break down stigma.
- Hims & Hers is seeking to highlight affordability and equity in healthcare.
- Experts say this trend is positive since it can help improve uptake of these medications.
- However, it’s essential that advertisers are responsible and accurate in their claims.
With 127 million pairs of eyes glued to TV screens in 2025 and ad revenue topping out at $650 million in 2024, Super Bowl advertising is big business, according to figures provided by Statista.
However, this year’s Super Bowl isn’t just about touchdowns and halftime theatrics; it’s also turning into a national conversation about healthcare.
Companies are using the Big Game’s unparalleled reach to promote GLP-1 medications such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound).
These medications are widely prescribed for type 2 diabetes and obesity and have become both medically transformative and culturally controversial.
One ad from telehealth company Ro, starring former professional tennis player Serena Williams, seeks to dismantle the stigma around these medications, while Hims & Hers is leaning into themes of healthcare affordability and accessibility, highlighting how access is often driven by wealth.
GLP-1 medications are an important development in healthcare
Ana Reisdorf, MS, who is a registered dietitian and founder of the website GLP-1 Hub, said that GLP-1 medications have been an important development in healthcare due to the prevalence of obesity and metabolic disease.
“These meds offer a very effective solution to this issue,” she said, adding that this is the first time in recent decades that the obesity rate has actually started to go down.
According to Gallup, the obesity rate has declined from a record high of 39.9% in 2022 to 37.0% in 2025.
Reisdorf went on to explain that these drugs help regulate appetite, blood sugar, and energy balance.
They also reduce the “food noise” that can make weight loss so difficult.
“Importantly, they also improve heart health, insulin resistance, blood pressure, and blood cholesterol,” she said.
“They are a miracle in a space that has been a struggle for so long,” Reisdorf added.
Why many people avoid GLP-1 medications despite the benefits
Timur Alptunaer, MD, of InHouse Wellness, noted, however, that despite the many benefits for metabolic health, people are often resistant to trying these medications because they see it as a personal failure if exercise and diet alone are not enough, a perception which he says is “damaging.”
“Obesity goes beyond lifestyle choices,” he said. “Obesity is a problem that is influenced by countless factors, including genetics, hormones, the environment, and the brain.”
Putting things into perspective, Alptunaer compared the use of obesity drugs to using insulin for diabetes or using blood pressure medications for hypertension, which he says is no different.
Alptunaer praised Ro’s ad starring Serena Williams, saying that having a well-known athlete as a spokesperson could help reduce some of the stigma surrounding GLP-1
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